Changes in expression of the CD200 tolerance-signaling molecule and its receptor (CD200R) by villus trophoblasts during first trimester missed abortion and in chronic histiocytic intervillositis (Clark DA, Dmetrichuk JM, McCready E, et al) – 2017
This paper looks at the immune response in a pregnancy in women with recurrent miscarriage and specifically CHI. It was a small study that only looked at a few placentas under the microscope and offers no clear solution or treatment but is important to show that ongoing research is happening looking at how the immune system can have an effect on pregnancy.